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Santacruzamate A 1477949-42-0

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Synonyms ：
Appearance ：
Chemical Formula ：
C15H22N2O3
Solubility ：
Molecular Weight ：
278.35
Storage and Stability ：
in stock
CAS No. ：
1477949-42-0
Purity ：
98%+
Introduction
Santacruzamate A (CAY10683) is a potent and selective HDAC inhibitor with IC50 of 119 pM for HDAC2, >3600-fold selectivity over other HDACs

Santacruzamate A inhibits the growth of HCT116 colon carcinoma cells and HuT-78 cutaneous T-cell lymphoma cells, with GI50 values of 29.4 μM and 1.4 μM, respectively. However, Santacruzamate A shows hypotoxicity to human dermal fibroblast cells (GI50 >100 μM).

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