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Molidustat 1154028-82-6

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Synonyms ：
Appearance ：
Chemical Formula ：
C13H14N8O2
Solubility ：
Molecular Weight ：
314.30
Storage and Stability ：
in stock
CAS No. ：
1154028-82-6
Purity ：
98%+
Introduction
In vitro, Molidustat induces the transcription of hypoxia-sensitive genes in HeLa, A549, and Hep3B cells. 

In healthy Wistar rats and cynomolgus monkeys, Molidustat (1.5 mg/kg, p.o.) induces dose-dependent production of EPO and erythropoiesis. In rats with gentamicin-induced renal anemiabe, Molidustat (5 mg/kg, p.o.) is also effective in raising hematocrit levels while stimulating endogenous EPO production without hypertensive effects.

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