LY2584702 1082949-67-4

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Synonyms

：

Appearance

：

Chemical Formula

：

C21H19F4N7

Solubility

：

Molecular Weight

：

445.42

Storage and Stability

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in stock

CAS No.

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1082949-67-4

Purity

：

98%+

Introduction

In HCT116 colon cancer cells, LY2584702 inhibits phosphorylation of the S6 ribosomal protein (pS6) with IC50 of 0.1-0.24 μM. LY2584702 has significant synergistic effects when combined with EGFR inhibitor erlotinib or with the mTOR inhibitor everolimus.
LY2584702 (12.5 mg/kg BID), demonstrates significant antitumor efficacy in both U87MG glioblastoma and HCT116 colon carcinoma xenograft models.

Products for scientific research use only

LY2584702 1082949-67-4

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LY2584702 1082949-67-4

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CAS No. ：

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