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Z-FA-FMK 197855-65-5

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Synonyms ：
Appearance ：
Chemical Formula ：
C21 H23 F N2 O4
Solubility ：
Molecular Weight ：
386.42
Storage and Stability ：
in stock
CAS No. ：
197855-65-5
Purity ：
98%+
Introduction
Z-FA-FMK inhibits the degradation of fibrillar collagen by fibroblasts and osteoclasts. Z-FA-FMK inhibits LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages. Z-FA-FMK efficiently blocks T cell proliferation induced by mitogens and IL-2 in vitro. 

Z-FA-FMK significantly increases pneumococcal growth in both lungs and blood in a mouse model of intranasal pneumococcal infection.  Z-FA-FMK blocks reovirus infection of Ras oncogenic tumours and host heart tissues in severe combined immunodeficiency mice. 

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