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Roxadustat (FG-4592)

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Synonyms ：
FG-4592
Appearance ：
Chemical Formula ：
C19H16N2O5
Solubility ：
DMSO 70 mg/mL (198.67 mM)
Molecular Weight ：
352.34
Storage and Stability ：
in stock
CAS No. ：
808118-40-3
Purity ：
98%
Introduction
FG-4592 is an oral inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase currently in clinical development for the treatment of anemia. FG-4592 stabilizes the activities of HIF, a cytosolic transcription factor, leading to activation of the genes associated with erythropoiesis, including erythropoietin and enzymes involved in iron metabolism.

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