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Y-320 288250-47-5

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Synonyms ：
Appearance ：
Chemical Formula ：
C27H29ClN6O2
Solubility ：
Molecular Weight ：
505.01
Storage and Stability ：
in stock
CAS No. ：
288250-47-5
Purity ：
98%+
Introduction
Y-320 also inhibits the production of IFN-γ and TNF-α by mouse CD4 T cells stimulated with IL-15, CXCL12, and anti-CD3 mAb.

Y-320 (0.3-3 mg/kg p.o.) ameliorates collagen-induced arthritis (CIA) in Mice with a reduction of IL-17 mRNA in arthritic joints, and also shows therapeutic effects on CIA in cynomolgus monkeys. Moreover, Y-320 shows a synergistic effect in combination with anti-TNF-α mAb on chronic-progressing CIA in mice. 

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