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WS6 1421227-53-3

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Synonyms ：
Appearance ：
Chemical Formula ：
C29H31F3N6O3
Solubility ：
Molecular Weight ：
568.59
Storage and Stability ：
in stock
CAS No. ：
1421227-53-3
Purity ：
98%+
Introduction
WS6 induces R7T1 cell proliferation with EC50 of 0.28 μM, and promotes β cell proliferation in rodent and human primary islets. Both Erb3 binding protein-1 and the IκB kinase pathway are confirmed to function in the mechanism of action of WS6.

In RIP-DTA mouse model of β cell ablation, WS6 (50 mg/kg p.o.) ameliorates diabetes, and induces concomitant increases in β cell proliferation and β cell number. 

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