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Tenovin-6 1011557-82-6

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Synonyms ：
Appearance ：
Chemical Formula ：
C25H34N4O2S
Solubility ：
Molecular Weight ：
454.63
Storage and Stability ：
in stock
CAS No. ：
1011557-82-6
Purity ：
98%+
Introduction
Tenovin-6 is a small molecule activator of p53 transcriptional activity.

Tenovin-6 is a more water-soluble analog of tenovin-1. Tenovin-6 acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 in vitro with IC50 of 21 μM, 10 μM, and 67 μM, respectively.

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