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Telotristat Etiprate 1137608-69-5

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Synonyms ：
Appearance ：
Chemical Formula ：
C27H26ClF3N6O3.C9H9NO3
Solubility ：
Molecular Weight ：
754.15
Storage and Stability ：
in stock
CAS No. ：
1137608-69-5
Purity ：
98%+
Introduction
Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.

Telotristat Etiprate (300 mg/kg p.o.) significantly reduces 5-HT in the gut and blood, but not brain 5-HT. Telotristat Etiprate (200 mg/kg p.o.) alleviates the severity of trinitrobenzene sulfonic acid (TNBS)-induced colitis with lower expression of some genes encoding inflammation-related cytokines and chemokines in mice. 

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