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SRPIN340 218156-96-8

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Synonyms ：
Appearance ：
Chemical Formula ：
C18H18F3N3O
Solubility ：
Molecular Weight ：
C18H18F3N3O
Storage and Stability ：
in stock
CAS No. ：
218156-96-8
Purity ：
98%+
Introduction
SRPIN340 inhibits SR phosphorylation by SRPK in Flp-In293 cells and promotes degradation of SRp75 in a dose-dependent manner, which subsequently inhibits HIV production. SRPIN340 dose (5 mg/mL) produces no abnormalities in chromosomal structure and chromosome number of CHO cells.  SRPIN340 suppresses in a dose-dependent fashion expression of a HCV subgenomic replicon and replication of the HCV-JFH1 clone in vitro. 

SRPIN340 inhibits CNV formation in a dose-dependent manner in vivo. SRPIN340 significantly decreases the protein levels of VEGF, MCP-1, ICAM-1, and consequently inhibits macrophage infiltration. 

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