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SGC-CBP30 1613695-14-9

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Synonyms ：
Appearance ：
Chemical Formula ：
C28H33ClN4O3
Solubility ：
Molecular Weight ：
509.04
Storage and Stability ：
in stock
CAS No. ：
1613695-14-9
Purity ：
98%+
Introduction
SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM in cell-free assays, respectively. Exhibits 40-fold and 250-fold selectivity for CBP over the first BRD of BRD4 (BRD4(1)) and BRD4(2) respectively.

As a CREBBP/EP300-selective chemical probe, SGC-CBP30 shows moderate cytotoxicity in U2OS cells and HeLa cells. 

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