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OTSSP167

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Synonyms ：
OTSSP-167
Appearance ：
Chemical Formula ：
C25H28Cl2N4O2
Solubility ：
DMSO 0.5 mg/mL warmed (1.02 mM)
Molecular Weight ：
486.16
Storage and Stability ：
in stock
CAS No. ：
1431697-89-0
Purity ：
99%
Introduction
OTSSP167 exhibits significant tumor growth suppression in xenograft studies using breast, lung, prostate, and pancreas cancer cell lines in mice by both intravenous and oral administration. In MDA-MB-231 model, intravenous administration of OTSSP167 at 20 mg/kg once every two days results in TGI of 73% The oral administration at 10 mg/kg once a day reveals TGI of 72%. OTSSP167 for multiple cancer types in dose-dependent and MELK-dependent manners with no or a little body-weight loss.

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