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N6022 1208315-24-5

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Synonyms ：
Appearance ：
Chemical Formula ：
C24H22N4O3
Solubility ：
Molecular Weight ：
414.46
Storage and Stability ：
in stock
CAS No. ：
1208315-24-5
Purity ：
98%+
Introduction
N6022 is a selective, and reversible inhibitor of S-nitrosoglutathione reductase (GSNOR) with IC50 of 8 nM and Ki of 2.5 nM. 

N6022 shows limited off-target activity and low cytotoxicity toward A549 epithelial lung cells. 

N6022 (30 mg/kg iv or po) reduces bronchoconstriction and pulmonary inflammation in a mouse model of asthma. 

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