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IM-12 1129669-05-1

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Synonyms ：
Appearance ：
Chemical Formula ：
C22H20FN3O2
Solubility ：
Molecular Weight ：
377.41
Storage and Stability ：
in stock
CAS No. ：
1129669-05-1
Purity ：
98%+
Introduction
IM-12 is a selective GSK-3β inhibitor with IC50 of 53 nM, and also enhances canonical Wnt signalling.

In hNPCs, IM-12 inhibits GSK-3β activity with IC50 of 3.8 μM and subsequently increases β-catenin concentration significantly. Through the activation of canonical Wnt signalling pathway, IM-12 promotes the neuronal differentiation of human neural progenitor cells. 

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