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HJC0350 885434-70-8

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Synonyms ：
Appearance ：
Chemical Formula ：
C15H19NO2S
Solubility ：
Molecular Weight ：
277.38
Storage and Stability ：
in stock
CAS No. ：
885434-70-8
Purity ：
98%+
Introduction
HJC0350 is a potent and selective EPAC2 inhibitor with IC50 of 0.3 μM, exhibiting no inhibition on Epac1.


HJC0350 selectively blocks cAMP-induced EPAC2 activation but do not inhibit cAMP-mediated PKA activation. In HEK293/EPAC2-FL cells, HJC0350 also inhibits 007-AM mediated cellular activation of EPAC2. [1]

 
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