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GNE-9605 1536200-31-3

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Synonyms
Appearance
Chemical Formula
C17H20ClF4N7O
Solubility
Molecular Weight
449.83
Storage and Stability
in stock
CAS No.
1536200-31-3
Purity
98%+
Introduction
GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor with Ki and IC50 of 2 nM and 19 nM, respectively.


GNE-9605 is highly potent against LRRK2 in both biochemical (Ki = 2.0 nM) and cellular (IC50 = 19 nM) assays. In vitro human MDR1 permeability data, GNE-9605 exhibits excellent brain penetration in higher species. [1]


 
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