EHop-016 1380432-32-5

1.Inquiries will be replied within 24 hours

2.We could supply various packages as you required

3.To protect the profit of our agents, price will not show on website, please send inquiries to get the price.

4.Fast delivery, goods arrive your office within 3 to 5 days

5.Please click "Inquiry" or "Email" below to get the price

Synonyms

：

Appearance

：

Chemical Formula

：

C25H30N6O

Solubility

：

Molecular Weight

：

430.55

Storage and Stability

：

in stock

CAS No.

：

1380432-32-5

Purity

：

98%+

Introduction

EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-435 and MDA-MB-231 cells, equally potent inhibition for Rac3.

Rac inhibition by EHop-016 increases the activity of the closely related Rho GTPase RhoA by a compensatory mechanism. In MDA-MB-435 cells, EHop-016 (2-5 μM) inhibits association of active Vav2 with Rac1(G15A) mutant fusion protein, and reduces Rac-regulated cell functions including lamellipodia formation and cell migration. In addition, EHop-016 inhibits cell viability of MDA-MB-435 cells with IC50 of 10 μM. [1] EHop-016 also inhibits KITD814V-induced growth in SM and AML patients-derived cells. [2]

Products for scientific research use only

EHop-016 1380432-32-5

Thank you for your company product support!

CAS No. ：

Product Name ：

Number ：

Your name：
*

Phone：

Email：
*

The company or laboratory name：
*

EHop-016 1380432-32-5

Thank you for your company product support!

CAS No. ：

Product Name ：

Number ：

Your name： *

Phone：

Email： *

The company or laboratory name： *

Your name：
*

Email：
*

The company or laboratory name：
*