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GlyH-101 328541-79-3
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C19H15Br2N3O3 |
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493.15 |
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in stock | ||||
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328541-79-3 |
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98%+ |
Introduction
GlyH-101 is a selective and reversible CFTR inhibitor with Ki of 4.3 μM.
GlyH-101 reversibly inhibits CFTR Cl- conductance in <1 min. [1] In rabbit isolated ventricular myocytes, GlyH-101 also blocks cardiac I(Cl.PKA) channels. [2] In transfected FRT (SLC26A9-FRT) cells, GlyH-101 inhibits SLC26A9-mediated Cl- currents. [3]