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6H05 1469338-01-9

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Synonyms
Appearance
Chemical Formula
C20H30ClN3O2S3.CF3COOH
Solubility
Molecular Weight
590.14
Storage and Stability
in stock
CAS No.
1469338-01-9
Purity
98%+
Introduction
6H05 is a selective, and allosteric inhibitor of oncogenic K-Ras(G12C).
 
6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras. [1]. Furthermore, 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors. [2]
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