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LY2584702 1082949-67-4

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Synonyms ：
Appearance ：
Chemical Formula ：
C21H19F4N7
Solubility ：
Molecular Weight ：
445.42
Storage and Stability ：
in stock
CAS No. ：
1082949-67-4
Purity ：
98%+
Introduction
LY2584702 is a selective, ATP-competitive p70S6K inhibitor with IC50 of 4 nM. Phase 1.

In HCT116 colon cancer cells, LY2584702 inhibits phosphorylation of the S6 ribosomal protein (pS6) with IC50 of 0.1-0.24 μM. LY2584702 has significant synergistic effects when combined with EGFR inhibitor erlotinib or with the mTOR inhibitor everolimus. 

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