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GSK-LSD1 2HCl 1431368-48-7

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Synonyms
Appearance
Chemical Formula
C14H22Cl2N2
Solubility
Molecular Weight
289.24
Storage and Stability
in stock
CAS No.
1431368-48-7
Purity
98%+
Introduction
GSK-LSD1 2HCl is an irreversible, and selective LSD1 inhibitor with IC50 of 16 nM, > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B).

GSK-LSD1 induces gene expression changes in cancer cell lines with average EC50 of < 5 nM and inhibits cancer cell line growth with average EC50 of < 5 nM. 

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