Fludarabine Phosphate 75607-67-9

1.Inquiries will be replied within 24 hours

2.We could supply various packages as you required

3.To protect the profit of our agents, price will not show on website, please send inquiries to get the price.

4.Fast delivery, goods arrive your office within 3 to 5 days

5.Please click "Inquiry" or "Email" below to get the price

Synonyms

：

Appearance

：

Chemical Formula

：

C10H13FN5O7P

Solubility

：

Molecular Weight

：

365.21

Storage and Stability

：

in stock

CAS No.

：

75607-67-9

Purity

：

98%+

Introduction

Fludarabine Phosphate is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.

Fludarabine Phosphate is converted to F-ara-ATP in cells and then incorporated into DNA in a self-limiting manner. Fludarabine Phosphate competes with dATP for incorporation into the A site of the extending DNA strand, which results in termination of DNA strand elongation. Human DNA polymerase α incorporates more Fludarabine Phosphate into DNA than polymerase δ. Fludarabine Phosphate completively inhibits DNA polymerase α and DNA polymerase δ with Ki of 1.1 μM and 1.3 μM, respectively. DNA polymerase δ is also able to excise the incorporated Fludarabine Phosphate from DNA in vitro.

Fludarabine Phosphate 75607-67-9

Thank you for your company product support!

CAS No. ：

Product Name ：

Number ：

Your name：
*

Phone：

Email：
*

The company or laboratory name：
*

Fludarabine Phosphate 75607-67-9

Thank you for your company product support!

CAS No. ：

Product Name ：

Number ：

Your name： *

Phone：

Email： *

The company or laboratory name： *

Your name：
*

Email：
*

The company or laboratory name：
*