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Roxadustat FG-4592 808118-40-3

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Synonyms ：
Appearance ：
Chemical Formula ：
C19H16N2O5
Solubility ：
Molecular Weight ：
352.34
Storage and Stability ：
in stock
CAS No. ：
808118-40-3
Purity ：
99%+
Introduction
Roxadustat (FG-4592) is an HIF-α prolyl hydroxylase inhibitor in a cell-free assay, stabilizes HIF-2 and induces EPO production. Phase 3.

FG-4592 is an oral inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase currently in clinical development for the treatment of anemia. FG-4592 stabilizes the activities of HIF, a cytosolic transcription factor, leading to activation of the genes associated with erythropoiesis, including erythropoietin and enzymes involved in iron metabolism. 

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