Otenabant CP-945598 686347-12-6

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Synonyms

：

Appearance

：

Chemical Formula

：

C25H25Cl2N7O.HCl

Solubility

：

Molecular Weight

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546.88

Storage and Stability

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in stock

CAS No.

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686347-12-6

Purity

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98%+

Introduction

Otenabant (CP-945598) HCl is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor. Phase 1.

CP-945598 HCl inhibits CB1 receptor with moderate unbound microsomal clearance, low hERG affinity, and adequate CNS penetration. [1] CP-945598 HCl has low affinity with Ki of 7.6 μM for human CB2 receptors.

Otenabant CP-945598 686347-12-6

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Otenabant CP-945598 686347-12-6

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