AMG319 1608125-21-8

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Synonyms

：

Appearance

：

Chemical Formula

：

C21H16FN7

Solubility

：

Molecular Weight

：

385.4

Storage and Stability

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in stock

CAS No.

：

1608125-21-8

Purity

：

98%+

Introduction

AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.

AMG319 inhibits anti-IgM/CD40L-induced B cell proliferation with IC50 of 8.6 nM and reduces pAkt level with IC50 of 1.5 nM. AMG319 also inhibits anti-IgD-induce CD-69 expression in HWB.

AMG319 1608125-21-8

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AMG319 1608125-21-8

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