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Vemurafenib 918504-65-1
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white powder | |||||
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C23H18ClF2N3O3S |
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489.92 |
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in stock | ||||
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918504-65-1 |
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99%+ |
Introduction
Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold.