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PF-4708671 1255517-76-0

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Synonyms ：
Appearance ：
white powder
Chemical Formula ：
C19H21F3N6
Solubility ：
Molecular Weight ：
390.41
Storage and Stability ：
in stock
CAS No. ：
1255517-76-0
Purity ：
99%+
Introduction
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. First S6K1-specific inhibitor to be reported.

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