Products
NMS-P118 1262417-51-5
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white powder | |||||
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C20H24F3N3O2 |
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395.42 |
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in stock | ||||
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1262417-51-5 |
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99%+ |
Introduction
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).