R428 (BGB324) 1037624-75-1

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Synonyms

：

Appearance

：

white powder

Chemical Formula

：

C30H34N8

Solubility

：

Molecular Weight

：

506.64

Storage and Stability

：

CAS No.

：

1037624-75-1

Purity

：

99%+

Introduction

R428 (BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective).

CAS: 1037624-75-1

R428 (BGB324) 1037624-75-1

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R428 (BGB324) 1037624-75-1

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