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ACP-196 1420477-60-6

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Synonyms ：
Appearance ：
white powder
Chemical Formula ：
C26H23N7O2
Solubility ：
Molecular Weight ：
465.51
Storage and Stability ：
CAS No. ：
1420477-60-6
Purity ：
99%+
Introduction
Acalabrutinib(ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.

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