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Entospletinib 1229208-44-9

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Synonyms
Appearance
white powder
Chemical Formula
C23H21N7O
Solubility
Molecular Weight
411.46
Storage and Stability
CAS No.
1229208-44-9
Purity
99%+
Introduction
Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13- to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.

CAS:  1229208-44-9

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