Apitolisib 1032754-93-0

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Synonyms

：

Appearance

：

white powder

Chemical Formula

：

C23H30N8O3S

Solubility

：

Molecular Weight

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498.6

Storage and Stability

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CAS No.

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1032754-93-0

Purity

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99%+

Introduction

Apitolisib (GDC-0980, RG7422) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTOR inhibitor withKi of 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Phase 2.

CAS: 1032754-93-0

Apitolisib 1032754-93-0

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Apitolisib 1032754-93-0

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