Dovitinib 405169-16-6

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Synonyms

：

Appearance

：

white powder

Chemical Formula

：

C21H21FN6O

Solubility

：

Molecular Weight

：

392.43

Storage and Stability

：

CAS No.

：

405169-16-6

Purity

：

99%+

Introduction

Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4.

CAS: 405169-16-6

Dovitinib 405169-16-6

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Dovitinib 405169-16-6

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CAS No. ：

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