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Tanzisertib(CC-930) 899805-25-5

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Synonyms
Appearance
white powder
Chemical Formula
C21H23F3N6O2.HCl
Solubility
Molecular Weight
484.9
Storage and Stability
CAS No.
899805-25-5
Purity
99%+
Introduction
CC-930 is kinetically competitive with ATP in the JNK-dependent phosphorylation of the protein substrate c-Jun and potent against all isoforms of JNK (Ki(JNK1) = 44 ± 3 nM, IC50(JNK1) = 61 nM, Ki(JNK2) = 6.2 ± 0.6 nM, IC50(JNK2) = 5 nM, IC50(JNK3) = 5 nM) and selective against MAP kinases ERK1 and p38a with IC50 of 0.48 and 3.4 μM respectively.

CAS:  
899805-25-5

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