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Neratinib

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Synonyms :
Neratinib
Appearance :
Chemical Formula :
C30H29ClN6O3
Solubility :
DMSO 2 mg/mL (3.59 mM)
Molecular Weight :
557.04
Storage and Stability :
20grams
CAS No. :
698387-09-6
Purity :
98%
Introduction
Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for HER2 and EGFR, respectively.Neratinib (HKI-272) is a tyrosine kinase inhibitor, it is a dual inhibitor of the human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.

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