Products
BGJ398 NVP-BGJ398 872511-34-7
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white powder | |||||
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872511-34-7 |
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560.48 |
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872511-34-7 |
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99.5% |
Introduction
BGJ398 (NVP-BGJ398) is a potent and selective FGFR inhibitor for FGFR1/2/3 with IC50 of 0.9 nM/1.4 nM/1 nM in cell-free assays, >40-fold selective for FGFR versus FGFR4 and VEGFR2, and little activity to Abl, Fyn, Kit, Lck, Lyn and Yes. Phase 2.